EXPERT & USER REVIEWS


Read our user reviews below and under each product page.

PLEASE NOTE: We have received and recorded many benefits related to a wide variety of medical conditions. We can only share some of them privately and confidentially for regulatory reasons. In addition, our products are the subject of various ongoing human clinical trials seeking clearance by the U.S. Food and Drug Administration (FDA) and other health authorities around the world for a variety of chronic and acute health conditions.

Please contact us and share your experience and results. We are excited to inform people about the great benefits of using D'OXYVA.

EXPERT REVIEW HIGHLIGHTS


USER REVIEW HIGHLIGHTS


USER REVIEWS







EXPERT REVIEW HIGHLIGHTS








D'OXYVA review Prof. Ito Puruhito MD It works well, proven by the improvement of the perfusion index (PI-Masimo) of the diabetic wounds of Grade Wagner-I and Wagner-2 after a series of 5 applications. We continued the work by measuring TcPO2 (SENTEC) in another group of 15 patients with the same protocol, whereby we can prove that the transdermal CO2 application of D'OXYVA results in wound treatment improvement.

PROF. ITO PURUHITO, THORACIC VASCULAR SURGEON (M.D., Dr. MED., FLCS, FCTS) INDONESIA

> Chairperson, Research Cooperation Affairs at Institute of Tropical Disease, Airlangga University Surabaya
> Chairperson, Ministry of Education and Culture, Rep. Indonesia, Board of Higher Education, Research Council
> Chairperson, Research Cooperation Affairs, Institute of Tropical Disease, Airlangga University Surabaya

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D'OXYVA review Prof. Judy Delp PhD Toriyama et al. studied the effect of CO2 bathing in 83 limbs with critical ischemia and achieved limb salvage in 83% without surgery. They concluded that peripheral vasodilation from CO2 bathing resulted from an increased parasympathetic and decreased sympathetic activity. Application of transdermal CO2 produces a remote vasodilation that may be mediated through release of a circulating humoral agent.

Recently, studies have documented that episodes of brief, non-damaging ischemia occurring in a tissue can induce systemic protection against ischemia-reperfusion injury in a remote organ. This phenomenon, termed remote ischemic conditioning, has been demonstrated to confer protection against ischemic events in the myocardium, brain, and kidney. Although shown to be effective in various clinical and pre-clinical models, the mechanism(s) of remote protection have not been clearly identified.

Both neural and humoral mechanisms have been proposed to contribute to the protection against ischemic damage afforded by remote ischemic conditioning. Basalay et al. have shown that when remote ischemic conditioning is applied before induction of myocardial ischemia, sensory nerves and recruitment of a parasympathetic neural pathway are involved in reduction of infarct size. Recently, Michelsen and colleagues have demonstrated that dialysate of human plasma from subjects who underwent either ischemic preconditioning or exercise preconditioning reduced infarct size in rabbit hearts, indicating that release of a humoral factor, contributes to the cardioprotective effects of ischemic and exercise preconditioning; however, these circulating substance(s) remain to be identified.

Future investigations will need to monitor heart rate, heart rate variability, and sympathetic nerve activity in order to more fully assess the role of the autonomic nervous system in mediating the sustained increases in SPP and systolic blood pressure reported in this initial study and focus on assessment of plasma samples during and following transdermal CO2 application. The D’OXYVA device is safe and can be administered at home. There are a lot of possibilities here and we are really excited about conducting future studies to determine what D'OXYVA may be able to provide to people with microvascular disease.

PROF. JUDY M. DELP, PHD, PROFESSOR OF BIOMEDICAL SCIENCES, UNITED STATES

> Professor of Biomedical Sciences
> Education B.S. Rockhurst University, Kansas City, Missouri
> Ph.D. University of Missour
> Member at the American Physological Soceity, American Microcirculatory Society, American Heart Association

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D'OXYVA review Dr. Jim Bledsoe PhD I have been using the D'OXYVA for past 4 years. After I started using the D'OXYVA, I felt a major improvement in my breathing because my sinus issues had cleared up. Second, I stopped snoring. After about 4 months, I realized that my muscles felt better and I was gaining my muscle mass back.

Then, I realized the varicose veins in my ankles had been reduced to less than 1/3 of it was. I have had a major reduction in pain and inflammation throughout my body. Now 4 years later, I feel physically stronger than I did 20 years ago. I am still increasing my muscle mass just by daily stretching, deep breathing and doing a D'OXYVA application three times weekly. I know that the D'OXYVA applications have caused my body to feel good again.

I have clients that have had similar and various results. One client has reported a major improvement in their eyesight. Six different clients have reported a reduction of varicose veins. A lot of clients have reported reduced amounts of inflammation and pain. Some clients have reported an increase in energy and endurance.

The fact is that the D'OXYVA increases the effectiveness of the Microcirculatory System. The body will feel better because of Microcirculatory System will improve the blood flow throughout the body. Increasing the blood flow will help the body heal itself.

I can highly recommend everyone should be doing D'OXYVA applications on a regular basis. You will be able to feel the difference.

DR. JIM BLEDSOE, PHD, NUTRITIONAL SCIENCE, UNITED STATES

> Holistic Practitioner (20 years)
> Reflexologist, Master Herbalist, Iridologist
> Clinics: Pensacola, FL and Jackson, MS

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D'OXYVA review Dr. Stefanie Williams At European Dermatology London we use the D’OXYVA device after non-surgical aesthetic procedures to help reduce the down-time for patients; and as part of our Medical-grade Pedicures for diabetic patients, who often suffer with impairments in their feet’s microcirculation.

DR. STEFANIE WILLIAMS, MD, DERMATOLOGIST, UNITED KINGDOM

> German Board Certified Dermatologist, GMC Registered Doctor
> Awarded the title of Specialist in Dermatology and Venereology by the Hamburg Medical Council
> Awarded the British Leverhulme and the French Rene Touraine
> Author and co-author of 100 scientific articles, book chapters and abstracts

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D'OXYVA review Dr. Stephen Pfeifer Circularity has a novel, affordable treatment for patients. The D'OXYVA delivery system can be purchased by the patient and they have it in their homes for the rest of their lives. They can then treat pets and family members with a 7 minute treatment per day for about the same daily cost as a Starbucks coffee. The cumulative benefits of using D'OXYVA daily are immeasurable in so many health conditions.

My experience with patients in my Functional medicine practice was that 7/10 patients felt an immediate calming effect after one treatment. We documented most patients had a five point drop in blood pressure and pulse decrease within five minutes of one treatment. I am intrigued with the new data physicians will be presented with the clinics' diagnostic platform. However, most doctors will have few treatment options to suggest other than diet and exercise and nutraceuticals.

Physicians who adopt D'OXYVA will be able to offer their patients with a novel, effective, affordable way to address these imbalances. And they can be delivered in the comfort of their own home. This is the perfect storm!

DR. STEPHEN PFEIFER, MD, UNITED STATES

> Integrative Health Centers Practice Developer and Physician
> Health and Wellness of Carmel Practice Physician
> American Health Network Independent Primary Care Physician
> Author and co-author of dozens of healthcare articles, book chapters and abstracts

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D'OXYVA review Prof. Endre Varga In every 30 seconds a diabetic lower limb is lost somewhere in the world. For this reason diabetes and wounds is a dangerous combination; therefore, the management can be difficult. The standard treatment of a diabetic wound includes accurate surgical debridement and controlling the diabetic metabolism, as well as eliminating the infection by means of antibiotic therapy. In our presented case an insulin-dependent diabetic patient was treated for trimalleolar ankle fracture combined with very serious soft tissue destruction.

After admission to our department the possible treatment options were amputation or a long-term combined surgical treatment. The patient underwent a very drastic surgical debridement, the necrotised skin was removed. Infection was diagnosed with the identified pathogens being Enterobacter cloacae and ludwigii, Acinetobacter sp., Proteus mirabilis and Escherichia coli. After microbiological consultation an adequate antibiotic treatment was introduced. Every two days we repeated the surgical debridement and we applied jet lavage. After ten days there were no further necrotised tissue so we continued with a VAC therapy for two weeks. With the assistance of a plastic surgeon we applied Integra® and after a few days a split-thickness skin graft. Patient’s compliance dropped off and needed psychological support. During episodes of confusion he removed the dressings and surprisingly after two weeks fly larvae (Diptera: Sarcophagidae) were found in the skin grafted area.

Then wound healing was accelerated by Bioptron® light therapy and D'OXYVA® (deoxyhemoglobin vasodilator) treatment was applied twice a day for 25 days. His wound nearly completely healed and closed after 25 days and he could walk with crutches. He was discharged home after three months of treatment.

CONCLUSION: Even a serious soft tissue damage can heal after applying adequate therapy, but in diabetic patients the decision is difficult. It is important to note that in order to avoid amputation, multidisciplinary approach is mandatory. The patient’s general condition, life expectancy, and compliance basically influence our decisions and during the treatment period we have to reassess the results and taking these factors into account, thus we can choose the best treatment option.

PROF. ENDRE VARGA, MD (HABIL), PHD (MED), HUNGARY

> Head of Central Operation Room and Sterilization Unit, Vice Chairman Trauma Department at University of Szeged Albert Szent-Gyorgyi Clinical Center
> Professor of Trauma Surgery
> Founder and Board Member ATLS European Commitee
> Author and co-author of hundreds of scientific articles, book chapters and abstracts

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D'OXYVA review Dr. Reinhard Bergel My wife and I definitely noticed a significant increase in vascular aerobic abilities and general vitality. In addition, we exercise aerobically every morning for 50 minutes in our hills and swim 30 minutes. We use this age-old method now available in a powerful advanced small device in the evening before going to bed and it's a fantastic boost.

DR. REINHARD BERGEL, PHD, INTERNATIONAL HYDROLOGY & SPA EXPERT, UNITED STATES

> University of Cologne M.S. Diplom Sportlehrer (exercise science-physical education & physical rehabilitation)
> University of California at Los Angeles M.S. Kinesiology
> University of California at Berkeley PhD (Education & Exercise Science)
> Co-author The Spa Encyclopedia and dozens of scientific articles, book chapters and abstracts

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USER REVIEW HIGHLIGHTS
































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USER REVIEWS








 
 
 
Pham H.
Date: 08-14-2016
I am from Vietnam. I just used D'oxyva around 5 weeks. It works very well. My hight pressure is reducing Without taking medicines. I was feeling a good mood after used D'oxyva. Thank you.
 
 
 
Kenneth Williams
Date: 08-02-2017
Its a breakthrough in Medical as its the first of its kind that improve microcirculation which indeed helps in recovery of numerous ailments. It makes you wonder such a simple thing makes a huge impact on your health.
 
 
 
Piroska D. from FL United States
Date: 10-24-2016
It's good for little headache And that's why you should start to use it! It's works for me!
 
 
 
Marcus T. from United States
Date: 10-16-2016
I suffered a major injury to my ankle requiring surgery. After getting the recommended dosage from Jennifer I was able to incorporate my treatments in line with what my doctor had me doing. A week after surgery I noticed the swelling was reduced significantly as well as noticeable healing of my incisions. I was able to decrease the dosage of my pain medication after only 4 days and ultimately was able to completely remove myself from the prescription pain medication after 7 days. My prescription was for 14 days. After each treatment I noticed a significant decrease in blood pressure as well as arise in my oxygen levels in my bloodstream. At the 2-week Mark I was able to start walking without the aid of my crutches. I honestly believe that the use of D'OXYVA significantly decreased my recovery time and allowed me to return to work 3 weeks sooner than my doctor anticipated. I would recommend this product to anyone dad wants to speed up recovery from injuries or surgery.
 
 
 
Sheryl T. Golconda, NV United States
Date: 06-21-2017
They were easy to get out of the box and put in and twist and take out and recycle. And they are to expensive.
 
 
 
Kate H.
Date: 09-20-2016
I have been using the D'oxyva for years. The varicose veins on my legs doesn't show as much or at all. I don't have to stretch in the morning, it gives me more energy during the day. Love it!
 
 
 
joohean
Date: 09-10-2016
I am from Malaysia and have been using D'Oxyva for about six months already. When I started using it I had sleep problem as sometimes I could not sleep well or even if I managed to sleep in the technical sense I felt lethargic in the day time. Since using D'Oxyva, my sleep has vastly improved and I feel more energetic in the day time and can concentrate on my work more than I could have managed all this time. My memory has also improved a lot. Thanks for D' Oxyva for bringing a better change to my health, stamina and productivity. I think everyone should use this product wherher for curing blood circulatory related disease or for enhancement of his bodily functions to improve productivity.
 
 
 
Jennifer Rose Boadilla - Pelaez
Date: 02-08-2017
D'OXYVA is an amazing innovation in healthcare!
 
 
 
Loyd Rhodes, Sacramento, CA United States
Date: 07-11-2013
My heartfelt thank you to Circularity management for their support before and after my heart attack. I firmly believe the collateral capillaries that have formed on my heart, bypassing the damage, is a direct result of my using the Circularity system. I'm very happy to report an increase from 15% to an estimated 30% in the injection fraction number( I believe that is the correct name) that has occurred since I left the hospital. The generous gift of treatment cartridges has allowed me to increase my daily usage to 2-3 times per day and the cardiologist now says I may be a candidate for bypass surgery. I will keep the company informed of my progress. Again THANK YOU CIRCULARITY for making it possible for me to write this letter.
 
 
 
Jesse Golden in Viva Glam Magazine
Date: 05-17-2014
This is a revolutionary hand held device that delivers CO2 into the body in a molecular form. It increases oxygen levels to areas that need it. I was recommended by someone to be somewhat of a Guinea pig for my chronic illness (rheumatoid arthritis).

I was amazed at how the swelling and stiffness in my joints went away and I had more energy!

The best part is they market this product also for its beauty benefits. It can help with acne, wrinkles, spider veins, stretch marks and cellulite! Check out Circularity!
 
 
 
Maison Medical Spa, Savannah, GA United States
Date: 02-01-2013
The device is awesome....I have never seen anything change the appearance of a spider vein like it did.
 
 
 
Teresa V. from Pasadena, CA United States
Date: 07-09-2013
This device is amazing. My skin has improved significantly and my energy level has increased. I have recommended this to many people and I have sold 10 for various reasons. One customer is using it for their dog with labored breathing. Everyone loves it!
 
 
 
Emery R. from Seattle, WA United States
Date: 07-12-2013
I have only positive things to say about the device. I feel more energetic and youthful. I also feel that I have more aerobic capacity when I am doing physical activities from bike riding and hiking to swimming. The device is very easy to use. It is non invasive and takes only a few minutes per treatment. Service has been great each time I have contacted the company. The D'OXYVA device is my secret weapon against aging!
 
 
 
Judy T. from Pollock Pines, CA United States
Date: 04-09-2013
I have found that after only two weeks of using the D'OXYVA system daily that my metabolism has increased and is helping me to lose weight. My sex drive has increased and I am sleeping better throughout the night.
 
 
 
Lillie M. W. from Pensacola, FL United States
Date: 07-11-2013
As an Esthetician, I noticed certain scar tissues are healing and the cut that I have is healing really fast. I am very happy with it.
 
 
 
The Herb Shop, DEBORAH T. from RIDGELAND, MS United States
Date: 07-10-2013
My vision seems to be a little clearer. I have been experiencing chemically induced asthma from noxious fumes from a Nail Salon next door. I noticed that when I am struggling to breath, I will do an application and my ability to breath is noticeably better. Also, I am sleeping better now.
 
 
 
Laura S.
Date: 10-05-2013
Just got a message from a friend who has been using this device for 3 days only! here's what she said.

"I am feeling great from doing the treatments. Total release of tightening from my Achilles tendon. I am totally amazed!
 
 
 
Maria A. from the United States
Date: 08-19-2013
I have problems with sleeping and it (D'OXYVA) really helps me to sleep. I started sleeping really quickly, it helps me a lot.
 
 
 
Anonymous from London, United Kingdom
Date: 12-01-2014
Normally I would lie low the day after the dermapen treatment and wouldn’t go out at all. However on Saturday, the day after my treatment, I woke to dramatically less redness than usual, less irritation and swelling. So much so that even my daughter remarked that I wasn’t very red. With a little bit of make up I even ventured out to the shops - something I would never normally do until the 2nd Day. I would say that my face looked , on day 1, what it would normally look like on day 3 after treatment.
 
 
 
Dr. Jim B. from Pensacola, FL United States
Date: 01-21-2014
I am seeing an increase in muscle mass due to the D'OXYVA. I feel great. Thanks, Dr. Jim
 
 
 
Laura S. from Santa Barbara, CA United States
Date: 08-16-2012
My husband and I both love this product. One benefit we did not expect was how great our skin looks! My spider veins have all but disappeared and my husband loves how he feels. Recovery from running has improved.



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