Still Using Skin Patches, Needles, and Pills? Switch Now to the Only Gentle, Rapid, Effective and Painless Solution Without Breaking the Barrier of Your Skin!

Optimize Blood Circulation for Significant Outcomes!


D'OXYVA® (deoxyhemoglobin vasodilator) biotechnology provides an inexpensive and simple method of solving the longstanding problem of delivering medication to the bloodstream through needles, which are highly invasive, or oral delivery, which often results in gastrointestinal (GI) tract absorption issues and loss of most of the active ingredients in medication.

Clearly, its complete noninvasiveness makes it a much more patient-friendly method than
painful needle-based injections.

The rate of transdermal (over the skin) drug delivery development and usage has tripled in recent years, but extremely widespread adoption has been hampered by a need for technology that is more effective in penetrating the skin’s multiple barriers. D'OXYVA represents a giant step forward in overcoming these obstacles, as well as other long-established problems with standard needle-based and oral methods.

Compared to traditional delivery methods, D'OXYVA promises painless and fully noninvasive and nontoxic delivery of far higher concentrations of medication more directly, more quickly, and with greater efficacy than traditional and competing medication delivery methods, while reducing adverse side effects. Competing transdermal technologies try passing active pharmaceutical ingredients (API) through the skin layers that limit the molecular sizes and create adverse side effects such as skin irritation or permanent tissue damage.


D'OXYVA’s unique skin microcirculation (skin perfusion pressure) solution uses a high purity and concentration of GMP-compliant purified medical Carbon Dioxide (CO2) and water vapor in a molecular form, sprayed gently on the skin surface. The resulting vapor solution is a so-called supersaturated gas vapor, adjusted to the pH of your skin. Human skin is oily and watery and CO2 readily dissolves in our skin in molecular form with the patented and patent-pending process unique only to D'OXYVA.

It wasn’t until Circularity Healthcare found a gentle, fast and effective way to deliver CO2 over the skin and over the counter that the real benefits could be discovered.

In various individual case studies, early pilot studies, and randomized, placebo-controlled, double-blind clinical trials, D'OXYVA has reproducibly recorded significantly improved and sustained vascular activity and blood flow enhancement in skin tissue, heart muscle, and other vital organs. Thus, it improved function of the (micro) circulatory and certain key parts of the neurological system, such as the autonomic nervous system (ANS).

Taking D'OXYVA daily, users have been reporting a number of health and cosmetic benefits besides significant improvemets in mild to severe conditions, including but not limited to:

    Relief from symptoms of microvascular complications

    Significantly increased cardiac function, physical fitness, endurance and strength, muscle size, body tone, faster recovery from sports injuries and surgical trauma

    Promoting and maintaining a healthy weight, improving general mobility, deeper, more restful sleep

    Significant improvement of mental acuity; concentration, problem solving, multitasking, eye-hand coordination, heightened stamina, energy, and focus while managing stress

    Improved vitals across the board during checkups with zero adverse event reports after years of regular use by people with various health, demographic, and ethnic backgrounds

Start taking D'OXYVA® just a few times a week and start your new life today!

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What it does

D'OXYVA® (deoxyhemoglobin vasodilator) is the only fully non-invasive, non-irritating, non-opioid, and completely painless, transdermal (over the skin) microcirculatory solution with industry-leading clinical research results that does not break the skin's barrier.

In short, based on current leading neurology, immunology, microvascular, and cellular oxygenation science, D'OXYVA is leading the field by quickly targeting to:

Significantly lower the risk of diabetes and cardiovascular complications

Provide complete healing of difficult wounds together with major pain relief and improved quality of life:

  • Detoxify the skin and body
  • Improve sleep
  • Stamina and skin health
  • Reduce inflammation
  • And much more for all kinds of people

Highlighted reviews

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"I am seeing an increase in muscle mass due to the D'OXYVA. I feel great. Thanks, Dr. Jim" - Dr. Jim Bledsoe from Pensacola, FL United States

"I have found that after only two weeks of using the D'OXYVA system daily that my metabolism has increased and is helping me to lose weight. My sex drive has increased and I am sleeping better throughout the night." - Judy Trocha from Pollock Pines, CA United States

How it works

D'OXYVA's soft vapor solution with GMP-compliant purified medical CO2 readily dissolves in a molecular form in the skin to increase skin perfusion pressure, microcirculation.

It is non-electrical, handheld, painless, fast, and easy to use with no adverse side effects, according to years of user feedback and the results of past clinical trials with D'OXYVA.

It is an affordable, stand alone and adjunct application locally and all over the body. Taking D'OXYVA is easy; hold it against your skin surface for 5 minutes total, like comfortably inserting your thumb or anywhere you are hurt.

Increased oxygen-rich microcirculatory tissue perfusion is widely reported in published clinical research to improve physiological processes including but not limited to wound, tissue healing and repair, athletic performance, stamina, sleep quality, skin health, and much more.

D'OXYVA has recorded instant, outsized, and sustained improvements of the autonomic nervous system (ANS) in the brain leading to major tissue perfusion, blood circulation in macro-, and microcirculation enhancement in controlled human clinical trials (Phase I to III). These benefits result in significant improvements of essential physiological processes and clinical outcomes.

Medical CO2 gas is a widely accepted so-called gasotransmitter acting as a natural vasodilator amongst other beneficial critical signaling funtions when delivered by D'OXYVA's patented and patent-pending process.

D'OXYVA delivers the highest possible concentration of CO2 and has been clinically studied to significantly increase lasting blood flow volume in the microcirculatory system.

In addition, increased microcirculation with CO2 is widely known to increase the perfusion of oxygen.

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