Optimize Blood Circulation for a Variety of Significant Outcomes!

In a landmark clinical study, D'OXYVA (deoxyhemoglobin vasodilator) recorded consistent blood pressure (BP) reduction of up to 25%* in all participants at all measured times during 4 hours—maintaining healthy BP among diabetic (both Type 1–2) and non-diabetic participants.

*Average results rounded for display, based on number of enrolled subjects in each clinical study with D'OXYVA.
Read D'OXYVA Clinical Evidence

Taking D'OXYVA is easy; hold it against your skin surface for 5 minutes total, like comfortably inserting your thumb or anywhere you are hurt.

Generally recommended by doctors:



Take it daily—in a few weeks significantly reduce the risks of:






    *Six years of excellent user feedback and over two dozen clinical studies demonstrated outsized results at clinics and at home with zero adverse events. For example, D'OXYVA® (deoxyhemoglobin vasodilator) has been recording significant results also as a varicose vein treatment while delivering major clinical outcomes for well over 90% of users. Average results rounded for display, based on number of enrolled subjects in each clinical study with D'OXYVA and user feedback.
    Read D'OXYVA Clinical Evidence

    **Individual results may vary. Ask your doctor before taking D'OXYVA. For prescription for medical use.
    Read D'OXYVA Regulatory Statements

    ***We will refund your entire D'OXYVA purchase price if you do not achieve any improvements (proof of purchase required, improvements of blood flow (perfusion index) measured from absolute baseline without taking D'OXYVA).
    Read Circularity's Return Policy

DOXYVA Dark Gray (DG) Complete Health Device (Zoom-in) | Non-invasive Non-Significant Risk (NSR) Transdermal (Over-the-Skin) Device 7011

People taking D'OXYVA have recorded significant improvements in cardiovascular activity leading to much improved physical activity.

D'OXYVA's platform solution acting as a catalyst for the body to heal and improve itself is vaporized ultra-purified medical and pharmaceutical carbon dioxide. Purified CO2 is a non-toxic pharmaceutical molecule cleared by the U.S. FDA, the European Medicines Agency, and nearly all drug regulatory agencies worldwide registered in their respective pharmacopeias.

    CO2 is a non-toxic substance according to the FDA and delivering it via transdermal means (over-the-skin) by D'OXYVA has demonstrated a much better and safer alternative route to inhalation, a routine delivery method in hospitals for anesthesia.

    D'OXYVA uses medical or pharmaceutical carbon dioxide and delivers it via its fully non-invasive transdermal delivery system.

    Our products are manufactured in compliance with the highest medical device standards (e.g., EN ISO13485:2012).

Are you burned out from too much travel and work?

Are you looking to boost your stamina and sleep better?

Are you in pain?

Do you have chronic, burn or trauma wounds healing slowly or not at all?

Check out the colors of D'OXYVA® devices and start your new life

As part of a healthy lifestyle, D'OXYVA may help significantly reduce the risk of high blood pressure, hypertension, cholesterol, and diabetes in just 2 or 3 months with taking it 5 times a week. Read other options to help your circulation in "Blood Flow vs Blood Circulation - Doctor Approved Methods".

Poor circulation is a gateway for a litany of ailments:

Slow Healing


Poor Complexion


Slow Metabolism

DOXYVA Turquoise (TQ) Complete Health Device (Zoom-in) | Non-invasive Non-Significant Risk (NSR) Transdermal (Over-the-Skin) Device 7011

Circularity's platform biotechnology carries virtually no health risks but much greater benefits and cost savings than other modalities.

Take D'OXYVA® Daily—Significantly Improve Your Health
in a Few Weeks

What it does

D'OXYVA (deoxyhemoglobin vasodilator) is the only fully non-invasive, non-irritating, non-opioid, and completely painless, transdermal (over-the-skin) microcirculatory solution.

With over five years of industry-leading clinical research results, D'OXYVA demonstrated that it does not break the skin's barrier while it provides outsized quality of life and clinical outcomes quickly and affordably.

In short, based on current leading neurology, immunology, microvascular, and cellular oxygenation science, D'OXYVA is leading the field by:

Significantly lowering the risk of diabetes and cardiovascular complications

Providing complete healing of difficult wounds together with major pain relief and improved quality of life

How it works

D'OXYVA's gentle vapor solution with purified medical CO2 readily dissolves in a molecular form in the skin, acting as a catalyst to improve skin perfusion pressure and optimize nerve functions and microcirculation.

Non-electrical, handheld, painless

Fast & easy use virtually anywhere

The Science

Improved parasympathetic nerve function and oxygen-rich microcirculatory tissue perfusion is widely reported in published clinical research to improve physiological processes and yield significant health benefits and clinical outcomes including, but not limited to:

Chronic, burn, trauma wound, tissue healing & repair

Boost cardiovascular, athletic performance, stamina, sleep quality

Fade spider & varicose veins, aid in skin health

Improve sleep, stamina, and skin health

Reduce inflammation, high blood pressure and blood sugar

D'OXYVA has recorded instant, outsized, and sustained improvements of the autonomic nervous system (ANS) in the brain, enhanced tissue perfusion and blood circulation in macro-, and microcirculation, chronic wound closure and balanced blood pressure in controlled human clinical trials (Phase I to III).

Purified, medical CO 2 gas is a widely accepted so-called gasotransmitter acting as a natural vasodilator amongst other beneficial critical signaling functions when delivered by D'OXYVA's patented and patent-pending process. D'OXYVA gently sprays a so-called supersaturated concentration of CO2 in a vapor form on the surface of the skin.

Read D'OXYVA Clinical Evidence

Shop All Products

Talk to a Representative

Back to Top ^