Optimize Blood Circulation for a Wide Variety of Significant Outcomes


D'OXYVA® (deoxyhemoglobin vasodilator) in various clinical trials has validated leading independent research results and demonstrated above-average results in improving a host of physiological functions at the same time.

People using D'OXYVA have recorded significant improvements in cardiovascular activity leading to much improved physical activity. As part of a healthy lifestyle, D'OXYVA may help significantly reduce the risk of high blood pressure, hypertension, cholesterol, and diabetes in just two or three months, with an average use of 5 minutes a day and 5 times a week.

Poor circulation is a gateway for a litany of ailments: slow healing, depression, poor complexion, sores, slow metabolism, and more.

D'OXYVA significantly improves sustained oxygen-rich microcirculatory blood flow locally and throughout the body. Its patented method of fully non-invasive, painless, and harmless transdermal delivery is unique only to D'OXYVA.


When used daily, D'OXYVA users have reported a number of health and beauty benefits, including but not limited to:

  • Relief from symptoms of microvascular complications
  • Significantly increased cardiac function, physical fitness, endurance and strength, muscle size, body tone, faster recovery from sports injuries and surgical trauma
  • Improved self-esteem via promoting healthy and radiant skin, complexion, dry skin relief, and acne reduction
  • Significant reduction in downtime from other skin treatments and cosmetic procedures when used in combination, reduction in the appearance of scars, cellulite, fat, spider veins and stretch marks
  • Promoting and maintaining a healthy weight, improving general mobility, deeper, more restful sleep
  • Significant improvement of mental acuity; concentration, problem solving, multitasking, eye-hand coordination, heightened stamina, energy, and focus while managing stress
  • Improved vitals across the board during checkups with zero adverse event reports after years of regular use by people with various health, demographic, and ethnic backgrounds

Check out the colors of D'OXYVA® devices and start your new life today!




D'OXYVA's platform solution acting as a catalyst for the body to heal and improve itself is purified and vaporized medical carbon dioxide (UN1013 CO2). Purified CO2 is a non-toxic pharmaceutical molecule cleared by the U.S. FDA, the European Medicines Agency, and nearly all drug regulatory agencies worldwide registered in their respective pharmacopeias. Read our regulatory statements.

CO2 is a non-toxic substance and delivering it via transdermal means by D'OXYVA has demonstrated a much better and safer alternative route to inhalation.

The transdermal route with Circularity's platform patented transdermal technology inherently carries much lower risks but much greater benefits and cost savings at the same time.




Circularity Healthcare fills its patented, GMP-compliant, mini EasyTwist Cartridges with medical carbon dioxide and delivers it via its D'OXYVA patented, fully non-invasive transdermal delivery device.

Our products are manufactured in compliance with the highest medical device standards, (e.g., EN ISO13485:2012) and D'OXYVA is a CE-marked Class I non-sterile, low risk medical device available to the public.




What it does


D'OXYVA® (deoxyhemoglobin vasodilator) is the only fully non-invasive, painless, and non-irritating transdermal solution with industry-leading clinical research results that does not break the skin's barrier.

D'OXYVA has recorded instant, outsized, and sustained improvements of the autonomic nervous system in the brain, tissue perfusion, blood circulation in macro-, and microcirculation in controlled human clinical trials (Phase I to III), resulting in significant improvements of essential physiological processes and clinical outcomes.

In short, based on current leading neurology, immunology, microvascular, and cellular oxygenation science, D'OXYVA is leading the field by quickly targeting to:

Significantly lower the risk of diabetes and cardiovascular complications

Provide complete healing of difficult wounds together with major pain relief and improved quality of life

Detoxify the skin and body

Improve sleep

Stamina and skin health

Reduce inflammation

And much more for all kinds of people.


How it works


D'OXYVA's soft vapor of water and CO2 readily dissolves in the skin to increase skin perfusion pressure or microcirculation.

It is non-electrical, handheld, painless, fast, and easy to use with no adverse side effects, according to years of user feedback and the results of past clinical trials with D'OXYVA.

It is an affordable, stand alone and adjunct application locally and all over the body. D'OXYVA only takes 5 minutes per application.

CO2 is widely accepted as a natural vasodilator.

D'OXYVA delivers the highest possible concentration of CO2 and has been clinically studied to significantly increase lasting blood flow volume in the microcirculatory system.

Increased microcirculation with CO2 is widely known to increase the perfusion of oxygen based on the Bohr effect.

Increased oxygen-rich microcirculatory tissue perfusion is widely reported in clinical research to improve physiological processes including but not limited to healing, performance, stamina, sleep quality, skin health, and much more.